Subject: IIDR eNews - February 26th, 2018

Issue 13 - February 26th, 2018
This Month at the IIDR 
Dundas Central Public School Children Learn More About Microbes

Tuesday marked another exciting day for grades 4 to 6 students from Dundas Central Public School, Hamilton. Hosted by the Let’s Talk Science outreach program in collaboration with McMaster Children & Youth University (MCYU) and the Michael G. DeGroote Institute for Infectious Disease Research (IIDR), over 100 students took an eventful field trip to McMaster’s Burke Science Building to learn about the human immune system, pathogens, and disease.

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Wright lab publishes Rox gene's unprecedented mechanism of rifamycin resistance in Cell Chemical Biology

Rox genes - or, rifamycin monooxygenases - are found in a variety of environmental bacteria, and are associated with the decomposition of the clinically important antibiotic rifampin. In a recent study in Cell Chemical Biology led by Dr. Kalinka Koteva and Dr. Georgina Cox of the Wright labthe team takes a closer look at the structure and mechanism of resistance of Rox isolated from Streptomyces venezualae to uncover a novel method of antibiotic detoxification. 

Is the flu shot 10% effective? Or 55%? Dr. Mark Loeb cuts through the confusion on CBC’s The Morning Edition

Every year, scientists must make a prediction as to which strains to put into the influenza vaccine. However, a perfect match is difficult to estimate, resulting in much confusion regarding just how effective the seasonal vaccine is. In an interview on CBC's The Morning Edition, IIDR’s Dr. Mark Loeb explains why this year's flu shot is resulting in especially conflicting efficacy numbers.

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"Rise of superbugs could make chemo impossible” - Dr. Lori Burrow's comments on CBC Radio's The Current

It is estimated that drug-resistant infections (DRIs) are responsible for more than 700,000 annual deaths worldwide, and that by 2050 they may kill more people than cancer. On CBC’s The Current, IIDR’s Dr. Lori Burrows comments on the many challenges that researchers face when trying to find viable solutions to DRIs, and discusses potential solutions that could help mitigate this devastating global health threat.

! Ms. Elizabeth Polvi, PhD candidate from the Department of Molecular Genetics at the University of Toronto, will be coming to McMaster University on Wednesday, March 14th from 12:30pm to 2:00pm to give a talk to IIDR trainees. Her presentation, entitled "Dissecting Mechanisms of Echinocandin Drug Resistance and Filamentation in the Fungal Pathogen Candida albicans", will be followed by a pizza networking lunch. Open to all IIDR and MIRC members and trainees. Room to be announced.

*Please RSVP through before Friday, March 9th.
Trainee Day Ambassadors are looking for suggestions for a Keynote Speaker for November's IIDR Trainee Day 2018. If you have a favourite female scientist that you would like to see present this year (from anywhere in the world!), please send your nominations to before Friday, March 2nd.
Upcoming Events
! Wednesday, March 7th: ID / IIDR Combined Joint Rounds
Dr. Zain Chagla & Dr. Hendrik Poinar
8:00am - 9:00am
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Wednesday, February 28th: Work In Progress (WIP) Seminar Series
Jessica Breznik “Examining immunological effects of diet-induced obesity in female mice
Hemisha Patel “The role of Dectin-1 in pulmonary fibrosis
9:00am - 10:00am
MDCL 3023
Wednesday, March 7th: Immunology & Infection Program (IIP) Seminar Series
David Perrin, Professor from the Department of Chemistry, University of British Columbia
“Meeting the challenge of kit 18F-labeling of complex molecules for PET imaging: Rapid, Wet, One-Step, HPLC-free Radiosynthesis"
9:00am - 10:00am
MDCL 3023
Wednesday, March 14th: IIDR Trainee Seminar & Networking Lunch
Elizabeth Polvi, PhD Candidate
Department of Molecular Genetics, University of Toronto
Dissecting Mechanisms of Echinocandin Drug Resistance and Filamentation in the Fungal Pathogen Candida albicans"
12:30pm - 2:00pm
*Room TBA

*Lecture followed by a pizza networking lunch. 
*Please RSVP through before Friday, March 9th.
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