Subject: IIDR eNews - March 29th, 2019

IIDR Newsletter - Issue 26
March 29th, 2019

In The News
2019 DBCAD/IIDR Research Funding Recipients and Summer Student Fellowships Announced!

"Multidrug resistance is probably the biggest threat that we have to modern medicine"

Shrimp containing antibiotic-resistant bacteria have been found in Canadian grocery stores. Dr. Gerry Wright weighs in on the issue in this CBC Marketplace investigationWatch Online >

"I couldn’t have done this kind of research in India." 

In this Nature career feature, virologist Dr. Arinjay Banerjee of Dr. Karen Mossman’s lab explains how he reached his decision to pursue his career goals in Canada. Learn More >

"There's a lot we don't know about neonatal immunology"

Dr. Jeffrey Pernica comments on a new international study that looks at how an infant's immunity changes during its first week of life. Learn More >

"It's nonsensical to have these products licensed by Health Canada"

Dr. Mark Loeb hopes the results of his study showing that homeopathic remedies have no immunization effect will help hesitant parents understand there are no alternatives to conventional vaccines.
Learn More >

Reports & Publications
Ratcheting up Lipopolysaccharide Transport

A 47-year-old mystery has been solved: how crucial components of the bacterial cell wall are transported irreversibly to their resting place in a cell membrane. McMaster IIDR's Dr. Russell Bishop explains this beautifully in his recent Nature News & Views editorial article.

This Journal of Biological Chemistry Editor's Pick paper by Dr. Sara Andres explores how the protein Ctp1 interacts with DNA during repair, forming a zipper between two DNA molecules that may stabilize the repair complex.
Old Drug, New Trick: Dr. Lori Burrows trains her biofilms to "sniff out" new antibiotics in her latest publication. 

Staphylococcus aureus is a major cause of healthcare-associated infections, and a growing percentage are methicillin-resistant (MRSA). Dr. Omar El-Halfawy and Dr. Eric Brown describe a screening platform that targets wall teichoic acids (WTA) - an important feature of MRSA resistance. Learn More >
Dr. Marie Elliot's team find that airborne bacterial compounds modulate microbial community dynamics by altering environmental nutrient profiles in this mBio Editor's Pick. 
Intelligent food packaging: Dr. Tohid Didar's research team review various technological advances that hold great potential in helping control food-borne illnesses. Learn More >

Dr. Dawn Bowdish Receives MSU Community Engagement Award

Congrats to Dr. Dawn Bowdish on receiving the Community Engagement Award at the 2019 MSU Teaching Award CeremonyDawn was granted this award in recognition of her ongoing community involvement, which includes the coordination of science-based youth outreach activities, talks with various community groups, and "donor appreciation days" for her research participants. Dawn was further recognized for her commitment to Lung Association - Ontario, with whom she helps organize initiatives to raise lung health awareness and money for lung research. Dawn was nominated by her PhD students Jessica Breznik & Dessi Loukov and Prof. Carl Richards, and presented the award by her undergraduate student, Danny Ma.
CARD Update - March 2019

The Comprehensive Antibiotic Resistance Database has been updated. This update includes Prevalence, Resistomes & Variants expansion to 82 pathogens (with the addition of Brucella abortus, B. ovis, B. canis, and B. mellitensis), 81,000+ resistomes, and 173,000+ AMR allele sequences based on sequence data acquired from NCBI on February 28th, 2019. Check out the CARD website here.

Events & Seminars
! Please note that there will be no ID / IIDR Rounds Seminar for the month of April. Rounds will resume on Wednesday, May 1st, 2019. Additional details to come.

You're Invited! The David Braley Centre for Antibiotic Discovery - Official Opening
Mon., June 24th, 10:00am - 12:00am, MDCL 1st & 2nd Floor

Please join us for the official opening of the David Braley Centre for Antibiotic Discovery, taking place on Monday, June 24th! The event will begin with an official announcement of the new Centre on the 2nd Floor of the MDCL (main corridor) and will follow with a lunch reception in the MDCL Atrium. 
Additional details, including RSVP instructions and the event program, will follow in the coming months.

A Demystifying Medicine Seminar by Health Sciences 4DM3 Students
Mon., April 1st, 2:30p.m. - 5:00p.m., HSC 1A6

In this Demystifying Medicine and Knowledge Translation event, 4DM3 students will present examples of their work during the 2019 winter semester. Each group will showcase and discuss how they created short videos aimed to enhance the understanding of various complex medical and scientific topics. This free event is open to all and refreshments will be served.

Biochemistry and Biomedical Sciences Seminar Series - Dr. Jean Lim
Tues., April 16th, 11:30a.m. - 12:30p.m., HSC 4E20

Dr. Jean Lim is Associate Professor of Microbiology & Co-Director of the Microbiology Multidisciplinary Training Area at the Icahn School of Medicine at Mount Sinai. She will be presenting a seminar called "Dengue, then Zika: a one-two punch” at April 16th's BBS Seminar Series. Here, Dr. Lim will evaluate how dengue virus immunity alters the pathogenesis of Zika virus in mice, and infection of Zika virus in human tissue based models.

IIDR/BBS Seminar - Dr. David Heinrichs
Thurs., April 18th, 10a.m. - 11a.m., HSC 4E20

The Michael G. DeGroote Institute for Infectious Disease Research and Department of Biochemistry and Biomedical Sciences will be hosting Dr. David E. Heinrichs on Thursday, April 18. Dr. Henrichs is a Professor in the Microbiology & Immunology Department at the University of Western Ontario and is set to give a lecture called “A new link between metabolism and virulence potential in Staphylococcus aureus”. Coffee and cookies will be served at 9:45am.

Crohn’s and Colitis Canada's 24th Annual Gutsy Walk
Sun., June 2nd, Confederation Park (Edgewater Pavilion) 585 Van Wagners Beach Rd., Hamilton

Cures for Crohn’s disease and ulcerative colitis are only steps away! Join Crohn’s and Colitis Canada on Sunday, June 2nd for their 24th Annual Gutsy Walk to walk, jog, or run towards a future free from Crohn’s and colitis. Learn more about this year's walk here.
Jobs & Opportunities
III Call for Advisory Board Members
Deadline: April 8th, 2019

The CIHR Institute of Infection and Immunity is looking to fill three positions on its Institute Advisory Board (IAB), as part of the CIHR 2019 IAB membership renewal cycle. While recruiting for those positions, the Institute is looking at filling gaps in the Board membership. Therefore, they encourage you to apply if you are:
  • an early career investigator
  • a virologist or microbiologist
  • a researcher in health services, or in social, cultural, environmental, and population health (pillars 3 and 4)
  • a community representative.
Find out more about the the CIHR and application guidelines here.
Post-Doctoral Fellow

Dr.’s Michael Organ and Christopher Boddy from the Department of Chemistry and Biomolecular SciencesUniversity of Ottawa are looking to recruit a postdoctoral fellow with expertise in biocatalysis and protein engineering to participate in an interdisciplinary project centered around the development of an enzyme-transition metal tandem catalysis system. Candidates with expertise in automation and the ability to work closely with synthetic organic chemists are preferred. If interested, please send a CV and letter of interest to organ[at]uottawa[dot]ca and cboddy[at]uottawa[dot]ca.
Faculty Position

The Department of Genetics, Cell Biology and Anatomy (GCBA) at the University of Nebraska Medical Center invites applications for for a tenure-leading, Assistant/Associate Professor position at the interdisciplinary area of ‘Bioinformatics and Human Microbiome’ to start Fall 2019. The incumbent will complement the existing strengths in genomics, metagenomics, infectious diseases, and bioinformatics at UNMC. They are seeking a dynamic faculty member who interfaces with crosscutting disciplines such as cancer, neuroscience, infectious diseases, precision medicine, etc. to integrate the human microbiome research applications. To find out more about this position, please contact babu.guda[at]unmc[dot]edu or visit the posting here.
Post-Doctoral Fellow

Dr. Stephanie DeWitte-Orr's team at Wilfrid Laurier University is seeking a Postdoctoral Fellow for a 1 year MITACS Accelerate funded project beginning April or May 2019. The individual will study how long double-stranded RNA modulates innate immune responses at the cellular level. Qualifications: PhD in the Biological Sciences; namely, Cell and Molecular Biology, Immunology or related field. In order to be considered, please send a current curriculum vitae including a publication list, the names of three references and a brief cover letter to sdewitteorr[at]wlu[dot]ca.
Junior Group Leader / Professor in Microbiology & Senior Professor in Microbiology

The VIB / KU Leuven Center for Microbiology in Leuven, Belgium is announcing 2 job positions in a stimulating international research environment with excellent peers that will help to support the new group leader, a state-of-the-art laboratory space and access to VIB core facilities. They are interested in applications from any microbiology-related discipline, including synthetic biology, metabolic engineering, metabolomics, systems biology, metagenomics, genomics & applied microbiology. Each position comes with an attractive salary and benefits scheme and an annual research stipend of at least 200k euro per year, plus full PI rights to tap into the Belgian and EU funding and fellowship schemes. Learn more about the positions and how to apply here.

Post-Doctoral Fellow or Research Scientist

IIDR member Dr. Zeinab Hosseini-Doust is looking for a postdoctoral fellow or research scientist to conduct phage display experiments including library construction and screening for high affinity binders, and troubleshooting technical problems. Qualifications include a PhD in Molecular Biology or related field and experience in Molecular Biology. Required Skill Set: Experience with RNA isolation, RT-PCR, cDNA, and Molecular Cloning, construction of cDNA libraries, DNA sequencing, bacterial and/or yeast expression and purification of proteins, strong organizational, documentation, and record keeping skills, and observational and troubleshooting skills. In order to be considered, please send your resume and a brief cover letter to doust[at]mcmaster[dot]ca.
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